October 1985 through March 1986 - Dr. Peter Bub of Germany serves as the first ESWL/Endourology fellow. Dr. Howard Winfield served a fellowship under Ralph V. Clayman in Endourology in 1985.

October 24, 1985 - The Dornier HM-3 lithotriptor was installed and the first kidney stone lithotripsy was performed in Missouri at Midwest Stone Institute.

October 25, 1985 - The original bylaws that brought Midwest Stone Institute officially into being were signed.

February 1986 - An outpatient protocol for kidney stone lithotripsy was established.

July 1986 - Midwest Stone Institute provides physician training in ESWL as the first AUA certified site in Missouri.

December 1986 - Mallinckrodt Institute of Radiology secures the right to investigate the second generation lithotriptor known as the Siemens Lithostar and perform their first treatment. This was the first Lithostar in the United States.

August 6, 1987 - The Missouri Health Facility Review Committee approved the agreement between Midwest Stone Institute and Mallinckrodt Institute of Radiology.

August 31, 1987 - Mallinckrodt Institute of Radiology signs the agreement with Midwest Stone Institute under a Certificate of Need ruling to enable Mallinckrodt to proceed with their FDA trials under the auspices of Midwest Stone Institute’s Certificate of Need. Midwest Stone Institute provides physician support, administrative support, billing & scheduling to the Lithostar at M.I.R..

June 1988 - Dr. Terri Monk does the first IV sedation treatment on the HM-3 at MSI. Subsequently, all HM-3 procedures are performed in this manner.

October 1988 - Siemens Lithostar, after IDE Trials through a joint effort of Mallinckrodt Radiology and Midwest Stone Institute, received FDA Approval.

August 1990 - The last month of treatment before Mallinckrodt Institute of Radiology sold its Siemens Lithostar to a foreign concern.

November 1990 - Midwest Stone Institute successfully adopts the use of the Jenkins/Gillenwater (University of Virginia) Stryker Frame adaptation for treatment of mid and lower ureteral stone on the Dornier HM-3.

1991 - Midwest Stone Institute is approved as the first site in the United States or Canada, for the FDA trials of the EDAP LT-02.

June 3, 1992 - The Missouri Health Facilities Review Committee CON granted a research exemption to Midwest Stone Institute for studies on the EDAP LT-02 lithotriptor.

Mid-June 1992 - EDAP LT-02 arrived in the United States.

March 8, 1993 - The first patient was treated on the EDAP LT-02.

March 1993 - Midwest Stone Institute received a determination of non-reviewability from the Certificate of Need Committee for our mobile lithotripsy project because it was below the financial thresholds of the CON rules.

April 1993 - Midwest Stone Institute purchased a mobile Dornier HM-3.

July 22, 1994 - The first Midwest Stone Institute mobile lithotripsy was performed. The mobile HM-3 unit is home based at Barnes Jewish West County Hospital.

1998 - Midwest Stone purchases a mobile LithoTron and Homium Lasers

August 1998 - Midwest Stone Institute begins participation in the FDA trial using the OssaTron® shockwave technology for musculoskeletal conditions

October 2000 - The FDA approves shockwave therapy for the treatment of chronic proximal plantar fasciitis using the OssaTron®.

March 12, 2002- FDA approves shockwave therapy for the treatment of chronic lateral epicondylitis.

2003 - The FDA approves shockwave therapy for the treatment of tennis elbow or lateral epicondylitis

2003 - Midwest Stone provides cryosurgery for the treatment of prostate and kidney cancers as another minimally invasive surgical procedure.

July, 2004- Midwest Stone Institute begins providing brachy therapy services

2006 MSI provides holmium ablation of the prostate services

To date over 12,000 patients have experienced the miracle of ESWL and ESWT, through the auspices of Midwest Stone Institute. In addition, Midwest Stone Institute has trained and certified over 400 physicians to provide ESWL therapy under the permission of the AUA training site committee. Lastly, since 1985, over 29 fellows in ESWL and Endourology have been supported and trained by Midwest Stone Institute; many of these young urologists have since taken posts in academic centers in the United States, Germany, Canada, Israel and Austria.